Leonardo Bonucci was forced off in the 41st minute against Lazio last night due to injury.
Juventus have confirmed that the centre-back injured his right ankle and has already begun recovery efforts.
Media reports suggest Bonucci will be out for around a month but Juve’s statement did not mention a return timetable.
Juve could turn out short handed at centre-back in Bonucci’s absence as Benatia is on his way out but Caceres will return to the Bianconeri.